Ferric Pyrophosphate Soluble

Description : Ferric Phosphate is a tan or yellowish white odorless powder. It is insoluble in water and soluble in mineral acids. It can be prepared by reacting sodium pyrophosphate with ferric citrate. It shows good bioaccesibility.

Ferric pyrophosphate (FePP) is a widely used iron source in food fortification and in nutritional supplements, due to its white colour, that is very uncommon for insoluble Fe salts. Although its dissolution is an important determinant of Fe adsorption in human body, the solubility characteristics of FePP are complex and not well understood. This report is a study on the solubility of FePP as a function of pH and excess of pyrophosphate ions. FePP powder is sparingly soluble in the pH range of 3–6 but slightly soluble at pH < 2 and pH > 8. In the presence of pyrophosphate ions the solubility of FePP strongly increases at pH 5–8.5 due to formation a soluble complex between Fe(III) and pyrophosphate ions, which leads to an 8–10-fold increase in the total ionic iron concentration. This finding is beneficial for enhancing iron bioavailability, which important for the design of fortified food, beverages, and nutraceutical products.

Highlights :

  • Excess of pyrophosphate ions strongly increases the solubility of ferric pyrophosphate at pH 5–8.5.
  • The increase in solubility is attributed to formation of soluble complexes between Fe (III) and pyrophosphate ions.
  • The ~10 fold increase in the concentration of ionic iron at pH 7–8.5, which is close to the one of the small intestine, is expected to be beneficial for enhancing iron bioavailability.


Product Name CAS No.
Calcium Borogluconate N.A.
Calcium Citrate FCC 5785-44-4
Calcium Disodium EDTA FCC 23411-34-9
Calcium Gluconate FCC 18016-24-5
Calcium Glycinate 35947-07-0
Calcium Lactobionate FCC 110638-68-1
Calcium Orotate Dihydrate 22454-86-0
Calcium Peroxide 65% 1305-79-9
Calcium Peroxide 75% 1305-79-9
Calcium Peroxide FCC 1305-79-9
Calcium Pyrophosphate FCC N.A.
Calcium Sulfate FCC 10101-41-4
Calcium Sulfate Pure 10101-41-4
Calcium Sulfate Tech. 10101-41-4
Carbamide Peroxide 124-43-6
Copper Citrate hydrate 866-82-0
Copper Gluconate FCC 527-09-3
Dried Magnesium Sulphate 15244-36-7
Dried Magnesium Sulphate Pure 10034-99-8
Ferric citrate 2338-05-8
Ferric Orthophosphate FCC 10045-86-0
Ferric Orthophosphate FCC (Heavy) 10045-86-0
Ferric Orthophosphate FCC (Heavy) – Jetomised 10045-86-0
Ferric Orthophosphate FCC (Light) 10045-86-0
Ferric Pyrophosphate (Fe 20-22%) 10058-44-3
Ferric Pyrophosphate (Fe 20-22%) Micronized 10058-44-3
Ferric Pyrophosphate FCC 10058-44-3
Ferric Pyrophosphate FCC (Fe 24-26%) 10058-44-3
Ferric Pyrophosphate FCC V – Micronized 10058-44-3
Ferric Pyrophosphate Fe 21% 10058-44-3
Ferric Pyrophosphate Soluble 1332-96-3
Ferric Pyrophosphate Technical 10058-44-3
Ferrous Citrate 23383-11-1
Ferrous Fumarate FCC 141-01-5
Ferrous Gluconate FCC 299-29-6
Ferrous Lactate FCC V (Dihydrate) 5905-52-2
Magnesium Aspartate 72231-13-1
Magnesium Carbonate USP 546-93-0
Magnesium Chloride (Anhydrous Pure) N.A.
Magnesium Glycinate N.A.
Magnesium Lactate Dihydrate 18917-93-6
Magnesium Orotate, Dihydrate N.A.
Magnesium Phosphate, Dibasic FCC 7792-75-4
Magnesium Phosphate, Tribasic FCC 7757-87-1
Magnesium Sulphate Monohydrate 14168-73-1
Manganese (II) Fumarate 85169-07-9
Manganese (II) Malate Dihydrate N.A.
Manganese (II) Succinate 637-82-1
Manganese (II) Succinate Dihydrate 637-82-1
Manganese Gluconate FCC 6485-39-8
Manganese Lactate Dihydrate 51877-53-3
Potassium Fumarate Dihydrate N.A.
Potassium Fumarate Dihydrate Pure 7704-72-5
Potassium Gluconate FCC 299-27-4
Potassium Magnesium Citrate N.A.
Potassium Malate 585-09-1
Potassium Maleate N.A.
Sodium Adipate Technical 7486-38-6
Sodium Aluminium Sulphate 10102-71-3
Sodium Antimony Gluconate IP N.A.
Sodium Fumarate Dibasic 17013-01-3
Sodium Fumarate Monobasic 7704-73-6
Sodium Gluconate FCC 527-07-1
Sodium Selenate Anhydrous 13410-01-0
Sodium Selenite 10102-18-8
Sodium Succinate Anhydrous Pure 150-90-3
Strontium Citrate Dibasic Anhydrous 813-97-8
Tetrasodium Pyrophosphate 7722-88-5
Zinc Aspartate N.A.
Zinc Citrate 546-46-3
Zinc Gluconate FCC 4468-02-4
Zinc Glycinate N.A.
Zinc Orotate, Dihydrate N.A.
Zinc Peroxide 1314-22-3